In this collection on the basis of various sources, collected in the course of the researches of archaeologists, orientalists, philologists, historians of culture (art-critics) 2700-year-old history of one of the biggest centers of urban culture in Central Asia - Nasaf-Nakhshab-Karshi has been considered. The are unique materials about formation of the city from the ancient time till present. Sociocultural changes, which took place in life of Kashkadarya region’s capital during period of independence, are widely enlightened.